BCBusiness

October 2025 – Generation Shift

With a mission to inform, empower, celebrate and advocate for British Columbia's current and aspiring business leaders, BCBusiness go behind the headlines and bring readers face to face with the key issues and people driving business in B.C.

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The Healing Better campaign has been made possible through generous in-kind contributions from the following sponsors: Rethink, Global BC, Canada Wide Media, Barlow Media, Outsider Editorial, Alter Ego, Sequioa Films, Katharine Petkovski, ACTRA, Kalum Ko, and Wave Productions. with certain types of CF. Dr. Quon's next research phase involves growing patient nasal cells in the lab and testing their response to Trikafta—work that could expand access to the drug and lead to future treatments for those who don't benefit from it. "Ultimately, we want to make CF stand for 'cure found'," he says. Trina spent most of her life planning her funeral. Now, she's able to plan her future. Since beginning Trikafta, Trina says life has never been better. She hasn't been hospitalized. She can travel, breathe, live. And she's finally pursuing her childhood passion: she's a veterinary assistant at an animal clinic. "The whole cystic fibrosis team is amazing. They treat me like family—I've always felt seen and taken care of." Helping patients breathe again: Dr. Bradley Quon and Trikafta St. Paul's Hospital is home to the largest adult cystic fibrosis clinic in the province, and its clinicians are working on a cure for this challenging disease. Every year of research adds a year of life to the patients living with CF. Clinician-scientists like Dr. Bradley Quon are paving the way for life- Dr. Quon, clinician-scientist, medical director of the CF Adult Care Program, and researcher at the Centre for Heart and Lung Innovation, has devoted his career to helping patients embark on a path to Healing Better. Since Trikafta's discovery, St. Paul's Hospital hasn't performed a single lung transplant for CF patients. "I wouldn't be here if it weren't for research," she says. "I really wasn't able to live before Trikafta, and all the people behind it. You can't put a price on the difference St. Paul's Hospital makes in people's lives." Trina's story is a powerful reminder of what's possible when compassionate care, research, and innovation come together. At St. Paul's Hospital, that's Healing Better. changing treatments—and an eventual cure. In 2018, he led a clinical trial for Trikafta that showed dramatic improvements in patient lung function, quality of life, and reduced hospitalizations. The trial helped secure Trikafta's approval in Canada and today, the drug is widely available—helping thousands of Canadians breathe easier. While Trikafta is a transformational drug, it's only approved for people 100,045 EMERGENCY DEPARTMENT VISITS 1,239 BABIES BORN 139 KIDNEY TRANSPLANTS 553,606 PATIENT VISITS 718 OPEN HEART SURGERIES 27 HEART TRANSPLANTS* St. Paul's Hospital 2025: THE NUMBERS BEHIND OUR CARE *St. Paul's Hospital is the only facility in B.C. to perform adult heart transplants

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